Cranberry proanthocyanidins have anti-biofilm properties against Pseudomonas aeruginosa
نویسندگان
چکیده
منابع مشابه
Cranberry proanthocyanidins have anti-biofilm properties against Pseudomonas aeruginosa
BACKGROUND Bacteria within a biofilm are phenotypically more resistant to antibiotics, desiccation, and the host immune system, making it an important virulence factor for many microbes. Cranberry juice has long been used to prevent infections of the urinary tract, which are often related to biofilm formation. Recent studies have found that the A-type proanthocyanidins from cranberries have ant...
متن کاملCranberry-derived proanthocyanidins impair virulence and inhibit quorum sensing of Pseudomonas aeruginosa
Bacteria have evolved multiple strategies for causing infections that include producing virulence factors, undertaking motility, developing biofilms, and invading host cells. N-acylhomoserine lactone (AHL)-mediated quorum sensing (QS) tightly regulates the expression of multiple virulence factors in the opportunistic pathogenic bacterium Pseudomonas aeruginosa. Thus, inhibiting QS could lead to...
متن کاملAnti-Biofilm Activities from Marine Cold Adapted Bacteria Against Staphylococci and Pseudomonas aeruginosa
Microbial biofilms have great negative impacts on the world's economy and pose serious problems to industry, public health and medicine. The interest in the development of new approaches for the prevention and treatment of bacterial adhesion and biofilm formation has increased. Since, bacterial pathogens living in biofilm induce persistent chronic infections due to the resistance to antibiotics...
متن کاملAnti-biofilm Activity of Selected Plant Essential Oils against Pseudomonas aeruginosa and Staphylococcus aureus
Antibiotic resistance is a crucial grievous menace to public health on a planetary scale as it plummet the effectiveness of treatment and increase morbidity and mortality (Cassandra et al., 2008). Highly resistant bacterial evolution resulted in the compromised use of new generation of antibiotics (Levy, 2002). Antibiotic resistance is due to an inherent ability of microorganism to form surface...
متن کاملAnti-Biofilm and Antivirulence Activities of Metabolites from Plectosphaerella cucumerina against Pseudomonas aeruginosa
This study reported the efficacy of the metabolites of Plectosphaerella cucumerina, one phyllosphere fungus from Orychophragmus violaceus, against Pseudomonas aeruginosa quorum sensing (QS) and QS-regulated biofilms. The minimum inhibitory concentration (MIC) of the ethyl acetate (EtOAc) extract from P. cucumerina against P. aeruginosa PAO1 was 1.25 mg mL-1. At sub-MIC concentrations, P. cucume...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMC Complementary and Alternative Medicine
سال: 2014
ISSN: 1472-6882
DOI: 10.1186/1472-6882-14-499